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human lung adenocarcinoma cell line  (ATCC)


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    Structured Review

    ATCC human lung adenocarcinoma cell line
    Human Lung Adenocarcinoma Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 258 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human lung adenocarcinoma cell line/product/ATCC
    Average 93 stars, based on 258 article reviews
    human lung adenocarcinoma cell line - by Bioz Stars, 2026-02
    93/100 stars

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    ATCC lung adenocarcinoma cell line h441
    The extracellular lactate dehydrogenase (LDH) released in the culture medium of <t>H441</t> (a) and HaCaT (b) at 1 day after X-ray irradiation and of SH-SY5Y (c) and HaCaT (d) at 1 day after 131 I-MIBG administration. The LDH released was increased in H441 treated with 10-Gy X-ray irradiation but HaCaT was unchanged for both 2-Gy and 10-Gy irradiation. LDH released from SH-SY5Y was significantly increased after administration of 0.37 MBq 131 I-MIBG, and the increase was greater with higher radioactivity. LDH released from HaCaT was not increased after administration of 0.37 MBq 131 I-MIBG but was predominantly increased at 1.85 and 3.7 MBq 131 I-MIBG. † P < 0.01 and * P < 0.05 versus the controls.
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    The extracellular lactate dehydrogenase (LDH) released in the culture medium of H441 (a) and HaCaT (b) at 1 day after X-ray irradiation and of SH-SY5Y (c) and HaCaT (d) at 1 day after 131 I-MIBG administration. The LDH released was increased in H441 treated with 10-Gy X-ray irradiation but HaCaT was unchanged for both 2-Gy and 10-Gy irradiation. LDH released from SH-SY5Y was significantly increased after administration of 0.37 MBq 131 I-MIBG, and the increase was greater with higher radioactivity. LDH released from HaCaT was not increased after administration of 0.37 MBq 131 I-MIBG but was predominantly increased at 1.85 and 3.7 MBq 131 I-MIBG. † P < 0.01 and * P < 0.05 versus the controls.

    Journal: Journal of Radiation Research

    Article Title: Release of HMGB1 from human-derived cancer and normal cells by internal targeted radiotherapy with 131 I- meta -iodobenzylguanidine

    doi: 10.1093/jrr/rraf034

    Figure Lengend Snippet: The extracellular lactate dehydrogenase (LDH) released in the culture medium of H441 (a) and HaCaT (b) at 1 day after X-ray irradiation and of SH-SY5Y (c) and HaCaT (d) at 1 day after 131 I-MIBG administration. The LDH released was increased in H441 treated with 10-Gy X-ray irradiation but HaCaT was unchanged for both 2-Gy and 10-Gy irradiation. LDH released from SH-SY5Y was significantly increased after administration of 0.37 MBq 131 I-MIBG, and the increase was greater with higher radioactivity. LDH released from HaCaT was not increased after administration of 0.37 MBq 131 I-MIBG but was predominantly increased at 1.85 and 3.7 MBq 131 I-MIBG. † P < 0.01 and * P < 0.05 versus the controls.

    Article Snippet: The human-derived lung adenocarcinoma cell line H441 (American Type Culture Collection, Manassas, VA, USA) and the human-derived neuroblastoma cell line SH-SY5Y were used as cancer cells in this study along with the human keratinocyte cell line (HaCaT) as normal cells.

    Techniques: Irradiation, Radioactivity

    The extracellular LDH released per cell, normalized for the number of total cells. The LDH released per cell was increased H441 (a) and HaCaT (b) at 1 day after 10-Gy X-ray irradiation. The LDH released per cell was significantly increased after 2-Gy X-ray irradiation in HaCaT. In addition, the LDH released per cell increased at all examined 131 I-MIBG radioactivity’s in SH-SY5Y (c), and the LDH released per cell increased at 1.85 and 3.7 MBq of 131 I-MIBG in HaCaT (d).

    Journal: Journal of Radiation Research

    Article Title: Release of HMGB1 from human-derived cancer and normal cells by internal targeted radiotherapy with 131 I- meta -iodobenzylguanidine

    doi: 10.1093/jrr/rraf034

    Figure Lengend Snippet: The extracellular LDH released per cell, normalized for the number of total cells. The LDH released per cell was increased H441 (a) and HaCaT (b) at 1 day after 10-Gy X-ray irradiation. The LDH released per cell was significantly increased after 2-Gy X-ray irradiation in HaCaT. In addition, the LDH released per cell increased at all examined 131 I-MIBG radioactivity’s in SH-SY5Y (c), and the LDH released per cell increased at 1.85 and 3.7 MBq of 131 I-MIBG in HaCaT (d).

    Article Snippet: The human-derived lung adenocarcinoma cell line H441 (American Type Culture Collection, Manassas, VA, USA) and the human-derived neuroblastoma cell line SH-SY5Y were used as cancer cells in this study along with the human keratinocyte cell line (HaCaT) as normal cells.

    Techniques: Irradiation

    The extracellular HMGB1 in the cultured medium of H441 (a) and HaCaT (b) at 1 day after X-ray irradiation, and SH-SY5Y (c) and HaCaT (d) at 1 day after 131 I- m -iodobenzylguanidine ( 131 I-MIBG) administration. HMGB1 release was significantly increased in H441 irradiated with 2-Gy and 10-Gy X-ray irradiation, but HaCaT was unchanged for both 2-Gy and 10-Gy. HMGB1 release was significantly increased after administering 1.85 MBq and 3.7 MBq of 131 I-MIBG, but was unchanged after all radioactivity. † P < 0.01 and * P < 0.05 versus the controls.

    Journal: Journal of Radiation Research

    Article Title: Release of HMGB1 from human-derived cancer and normal cells by internal targeted radiotherapy with 131 I- meta -iodobenzylguanidine

    doi: 10.1093/jrr/rraf034

    Figure Lengend Snippet: The extracellular HMGB1 in the cultured medium of H441 (a) and HaCaT (b) at 1 day after X-ray irradiation, and SH-SY5Y (c) and HaCaT (d) at 1 day after 131 I- m -iodobenzylguanidine ( 131 I-MIBG) administration. HMGB1 release was significantly increased in H441 irradiated with 2-Gy and 10-Gy X-ray irradiation, but HaCaT was unchanged for both 2-Gy and 10-Gy. HMGB1 release was significantly increased after administering 1.85 MBq and 3.7 MBq of 131 I-MIBG, but was unchanged after all radioactivity. † P < 0.01 and * P < 0.05 versus the controls.

    Article Snippet: The human-derived lung adenocarcinoma cell line H441 (American Type Culture Collection, Manassas, VA, USA) and the human-derived neuroblastoma cell line SH-SY5Y were used as cancer cells in this study along with the human keratinocyte cell line (HaCaT) as normal cells.

    Techniques: Cell Culture, Irradiation, Radioactivity

    The extracellular HMGB1 released per cell, normalized for the number of total cells. The HMGB1 released per cell was increased in H441 (a) and HaCaT (b) at 1 day after 10-Gy X-ray irradiation. The HMGB1 released per cell was significantly increased after 2-Gy X-ray irradiation. In addition, the HMGB1 released per cell increased at 1.85 and 3.7 MBq of 131 I-MIBG in SH-SY5Y (c) and HaCaT (d).

    Journal: Journal of Radiation Research

    Article Title: Release of HMGB1 from human-derived cancer and normal cells by internal targeted radiotherapy with 131 I- meta -iodobenzylguanidine

    doi: 10.1093/jrr/rraf034

    Figure Lengend Snippet: The extracellular HMGB1 released per cell, normalized for the number of total cells. The HMGB1 released per cell was increased in H441 (a) and HaCaT (b) at 1 day after 10-Gy X-ray irradiation. The HMGB1 released per cell was significantly increased after 2-Gy X-ray irradiation. In addition, the HMGB1 released per cell increased at 1.85 and 3.7 MBq of 131 I-MIBG in SH-SY5Y (c) and HaCaT (d).

    Article Snippet: The human-derived lung adenocarcinoma cell line H441 (American Type Culture Collection, Manassas, VA, USA) and the human-derived neuroblastoma cell line SH-SY5Y were used as cancer cells in this study along with the human keratinocyte cell line (HaCaT) as normal cells.

    Techniques: Irradiation